Manchester NMR Methodology Group

Summary:
PROJECT allows for the measurement of T₂ weighted spectra without J-modulation. This is achieved by using a 90° refocusing pulse in-between a double spin echo. This suppresses J modulation by exchanging coherence between spins so that modulation caused in the first part of the double spin echo is refocused in the second half.

Pulse sequence:
The pulse sequence uses a “perfect echo” where a 90° pulse is inserted inbetween a double spin echo to refocus J-modulation. The counter n is increased attenuation of the signals present in a spectrum.

Downloads:
Bruker pulse sequence:
PROJECT (right click and chose 'save ... as')
Varian pulse sequence:
PROJECT (right click and chose 'save ... as')

Experimental data:
Bruker Captopril (right click and chose 'save ... as')

Varian Captopril (right click and chose 'save ... as')
Reference:
J.A. Aguilar, M. Nilsson, G. Bodenhausen, G. Morris, Chem. Commun.,2012,48,811-813
DOI: 10.1039/C1CC16699A

Please note that copyright restrictions prevent us from placing the pdf files on our website, however, this article is open access and the pdf can be downloaded from RSC.