Manchester NMR Methodology Group

Our primary interest is in the development of improved NMR techniques, but we also collaborate on a wide range of applications of NMR in chemistry, biochemistry, pharmacy and medicine - not just for their intrinsic interest, but also because testing the limits of current methods is a powerful source of inspiration for their improvement. Some recent collaborations are listed below.

Solà, J, Morris GA, Clayden J. 2011. Measuring Screw-Sense Preference in a Helical Oligomer by Comparison of 13C NMR Signal Separation at Slow and Fast Exchange. Journal of the American Chemical Society. 133(11):3712-3715

Villanueva, RD, Sousa AMM, Gonçalves MP, Nilsson M, Hilliou L. 2010. Production and properties of agar from the invasive marine alga, Gracilaria vermiculophylla (Gracilariales, Rhodophyta). Journal of Applied Phycology. 22(2):211-22

Khajeh, M, Bernstein, MA, and Morris, GA, 2010. A Simple Flowcell for Reaction Monitoring by NMR. Magnetic Resonance in Chemistry 48: 516-522.

Clayden, J, Castellanos A, Solà J, and Morris GA. 2009. Quantifying end-to-end conformational communication of chirality through an achiral peptide chain. Angewandte Chemie, International Edition, 48(32): 5962-5965.

van Lokeren, L, Willem R, van der Beek D, Davidson P, Morris GA and Ribot, F. 2010. Probing the Anions Mediated Associative Behavior of Tin-12 Oxo-Macrocations by Pulsed Field Gradient NMR Spectroscopy. J. Phys. Chem. C 114, 16087-16091

Arthurs, CL, Morris GA, Piacenti M, Pritchard R, Stratford IJ, Tatic T, Whitehead RC, Williams KF, and Wind NS, 2010. The synthesis of 2-oxyalkyl-cyclohex-2-enones, related to the bioactive natural products COTC and antheminone A, which possess anti-tumour properties. Tetrahedron 66, 9049-9060 (2010).

Mobli, M, Nilsson M, Almond A. 2008. The structural plasticity of heparan sulfate NA-domains and hence their role in mediating multivalent interactions is confirmed by high-accuracy 15N-NMR relaxation studies. Glycoconjugate Journal. 25(5):401-414.

Lapenna, S, Bilia AR, Morris GA and Nilsson M. 2009. Novel artemisinin and curcumin micellar formulations: drug solubility studies by NMR spectroscopy. J. Pharm. Sci. 98, 3666-3675.

Hassanzadeh, A, Barber J, Morris GA and Gorry PA. 2007. Mechanism for the Degradation of Erythromycin A and Erythromycin A 2´-Ethyl Succinate in Acidic Aqueous Solution. J. Phys. Chem. A, 111, 10098-10104