THE STRUCTURE OF ERYTHROMYCIN-A IN H-2(6) DMSO AND BUFFERED D2O - FULL ASSIGNMENTS OF THE H-1 AND C-13 NMR-SPECTRA

TitleTHE STRUCTURE OF ERYTHROMYCIN-A IN H-2(6) DMSO AND BUFFERED D2O - FULL ASSIGNMENTS OF THE H-1 AND C-13 NMR-SPECTRA
Publication TypeJournal Article
Year of Publication1991
AuthorsBarber, J, Gyi JI, Lian LY, Morris GA, Pye DA, Sutherland JK
JournalJournal of the Chemical Society-Perkin Transactions 2
Pagination1489-1494
ISBN Number0300-9580
Accession NumberWOS:A1991GK05500005
Abstract

The H-1 and C-13 NMR spectra of erythromycin A in [H-2(6)]-DMSO and buffered D2O have been assigned using a range of one and two dimensional NMR techniques. Assignments have been made for both the major (keto) and minor forms of the drug, and the minor form has been shown to be the 12,9-cyclic hemiacetal.

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