Manchester NMR Methodology Group

The addition of co-solutes to aid the separation of signals from molecules of similar size in DOSY experiments - matrix-assisted DOSY - is a potentially powerful technique for mixture analysis. The additional signals introduced by a co-solute can however greatly complicate analysis. By suitable choice of sample conditions{,} the NMR peaks of a surfactant matrix can be suppressed{,} allowing the clear resolution of molecular species according to chemistry and structure{,} without extraneous interference.